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Clinicians should consider checking serum bicarbonate at baseline and periodically during treatment, particularly in patients with renal impairment, those following a ketogenic diet, or those taking other carbonic anhydrase inhibitors

Infections often return after treatment, and long-term use increases the risk of drug resistance

Increased market competition could reduce prices and improve access, although manufacturing complexity may limit how low prices fall initially

With a BMI over 30, Jai went to her NHS doctor and asked if there was anything that could be done

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Pricing pressures, climate change, geopolitical conflict and recession risks all loom over the food and beverage industries