Those with more body fat can use 90 degrees (straight in), while leaner individuals may prefer 45 degrees to ensure the injection stays in the subcutaneous layer
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Then, keep up with injections every 1-3 months
Subcutaneous (into the fat just under the skin)
Wellness 20 July 2025 7 min read Needle Size for a B12 Injection: A Simple Guide By Alaiyka Parvez Owner, CoLaz Aesthetics Clinic The short version For an intramuscular B12 injection, the usual choice is a 22 to 25 gauge needle, 1 to 1.5 inches long, given at 90 degrees into the deltoid
That being said, the conversion of severe anemia to normal production of red blood cells can temporarily lead to low potassium levels and a high platelet count