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La presencia de torneos temporales, misiones semanales y clubes de fidelidad con niveles escalonados eleva el atractivo, ya que permite a los usuarios convertir su actividad en recompensas tangibles
Dosing increases gradually: Treatment begins with a low dose and steps up slowly so the body has time to adjust
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SGLT2 inhibition reduces glucose reabsorption at the level of the proximal renal tubule, promotes urinary glucose excretion independent of insulin action, and causes a negative caloric balance ( Figure 1 )
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The Diabetic Neuropathy symptom score consists of 4 questions assessing pain, numbness, tingling and ataxia
