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Ultimately, available evidence suggests that the long-term safety profile of GLP-1 receptor agonists remains favorable for most patients who tolerate therapy during the early stages of treatment

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Sources of Funding This research did not receive any specific grant from funding agencies in the public, commercial, or notforprofit sectors

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Of note, a small number of cases of acute pancreatitis associated with GLP-1RA use have been reported in clinical trials: 38 cases in 17,775 patient-years of exposure compared with 9 events in 5863 patient-years of exposure with the comparator treatment