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Classical RAAS cascade gives rise to the production of angiotensin II (Ang II) which binds to the Ang II type 1 receptor leads to vasoconstriction, cell proliferation, inflammation, increased oxidative stress and cell apoptosis [44]

Liu C, Teng ZQ, Santistevan NJ, Szulwach KE, Guo W, Jin P, et al

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Nicolay JP, Schneider J, Niemoeller OM, Artunc F, Portero-Otin M, Haik G Jr., et al