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With GLP-1 medications like semaglutide and tirzepatide, most people tolerate them well, but there are some things worth knowing upfront so you are not caught off guard
Gallbladder disease : Cholelithiasis (gallstones) and cholecystitis have been reported and may be common
However, they have also offered new insights into the power of our own gut hormones
The following sources are referenced in this article: Bannai, Seikatsu Eisei 2006 Dong, Evid Based Complement Alternat Med 2012 Eisenberg, Nat Med 2018 Elhassan, bioRxiv 2019 preprint Gomes, Cell 2013 Husain, Amino Acids 2020 Johnson, Ageing Res Rev 2023 Kiechl, Am J Clin Nutr 2018 Maric, Biosens Bioelectrol 2022 Massudi, PLoS One 2012 Messina, Adv Exp Med Biol 2000 Nowotarski, Expert Rev Mol Med 2013 Poljsak, J Clin Exp Oncol 2016 Saleh, bioRxiv 2024 preprint Shiojima, J Funct Foods 2024 Singh, Science 2023 Sorrenti, Mar Drugs 2020 Tavenier, Mech Ageing Dev 2024 Ulpathakumbura, Ageing Res Rev 2026 Woods, Eur Neuropsychopharmacol 2012 Wu, Eur J Clin Pharmacol 2005 Xu, Aging Dis 2017 Yin, Metabolism 2008 Join over 300,000 people on our weekly email list.
Manage Stress: Stress can lead to emotional eating
Distinguishing Between Sleep Disruption Causes and Root-Cause Solutions Not all semaglutide-related sleep changes warrant melatonin
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