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Prescriptions of the newer anti-hyperglycemic agents continue to stagnate, even among eligible patients [19], which may be related, at least in part, to the uncertainty about the optimal clinical management of T2D

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DOI: 10.1093/ndt/gfv409 57

Most can be managed with dose adjustments, supportive care, or simple lifestyle changes

Abbreviations DPP-4: Dipeptidyl peptidase IV EndMT: Endothelial-mesenchymal transition GLP-1: Glucagon-like peptide-1 H&E: Hematoxylin and eosin HUVECs: Human umbilical vein endothelial cells Li: Liraglutide MCT: Monocrotaline MTS: Masson trichrome staining PH: Pulmonary hypertension PSR: Picrosirius red staining PVR: Pulmonary vascular remodeling RVSP: Right ventricular systolic pressure SG: Sitagliptin T&I: TGF-1 combining IL-1 TB: Toluidine blue References Lai YC, Potoka KC, Champion HC, Mora AL, Gladwin MT