Success so far seems to be much higher than naltrexone but I have a limited number of patients and time that I have turned that with comparatively. - From a CASPR interview with an MD about semaglutide for AUD If upcoming studies confirm existing data, GLP-1 drugs will be, by a wide margin, the most widely deployed anti-addiction medications
For a family medicine and cannabis-medicine practice, that distinction is the clinical takeaway: a treatment can ease a symptom and still fall short of the rehabilitation goal that brought the patient into care, which is exactly the kind of honest gap analysis this specialty needs
If injections arent your thing, Rybelsus offers an alternative as the only oral tablet in the GLP-1 category
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Most patients adapt to semaglutide within 4-6 weeks, with gastrointestinal tolerability improving as the body adjusts to the medication's effects on digestion