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10.1016/j.biopha.2024.116222 14 ChenZ.HouR.ZhangY.XiongM.ZhangD.DingC
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In one melanoma study, mice exposed to higher NAC doses experienced greater metastatic activity than those given lower doses, suggesting the effect may be dose-dependent in certain experimental settings.42 Researchers have not established whether these findings apply to humans, but starting with a moderate dose offers a more conservative approach while still aligning with a large portion of the clinical literature
Consistent with these structural features, sequence alignment indicates that the key residues forming the ABCB7-CoPP interaction network are not well conserved in ABCB10 (Fig
