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Archives of Internal Medicine

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cohort study.25 Cardiovascular (CV) events Following the post-authorization ORAL Surveillance trial of tofacitinib in rheumatoid arthritis,29 it was recognized that JAK inhibitors may increase the risk of thrombosis, major adverse cardiovascular events (MACE), malignancy, and mortality in high-risk populations.30,31 However, it is unclear whether these risks apply to ritlecitinib in AA