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Weeks seven through twelve show continued weight loss at a steady rate, with appetite suppression remaining consistent and side effects typically resolving

The gradual dose increase helps reduce side effects, particularly the common digestive issue, when starting treatment

Therefore, glutathione, itself, is not very effective for use in supplements

However, it has been shown that mice have several more putatively functional CYP genes and pseudogenes than humans 97

Over time, insulin sensitivity improves, inflammation decreases, and appetite regulation becomes more stable

Studies are underway to better understand why this happens