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Am J Physiol Endocrinol Metab 313(6):E651E662 Hahn TM et al (1998) Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons

Consistent with this observation, glutamine starvation has been associated with impaired uptake of cystine through xCT and decreased intracellular glutathione levels 62

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Adding GIP enhances fat metabolism and improves insulin sensitivity, which is why tirzepatide outperforms semaglutide on weight loss