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The International Association for the Study of Pain defines it as pain resulting from a stimulus that does not normally provoke pain, and that definition matters because it distinguishes allodynia from hyperalgesia, where painful stimuli simply hurt more than expected

Mesenchymal stem cells alleviate the early brain injury of subarachnoid hemorrhage partly by suppression of Notch1-dependent neuroinflammation: involvement of Botch

Liu, Ann

Assays, biomarkers, and phenotypic endpoints Biochemical and transcriptional readouts ERR target-gene panels spanning fatty-acid uptake/-oxidation (Cpt1b, Acadl/Acadm), OXPHOS (Ndufs, Uqcrc, Cox), TCA (Cs, Idh), and mitochondrial biogenesis (Ppargc1a, Tfam) provide proximal pharmacodynamic evidence of receptor engagement

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A., Modu, B., Calina, D., & Sharifi-Rad, J