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Watowichs research group at the University of Texas Medical Branch (UTMB) at Galveston as a selective inhibitor of the metabolic enzyme nicotinamide N-methyltransferase (NNMT)
Additionally, weight loss itself may reduce systemic inflammation and improve cerebrovascular function, potentially slowing cognitive decline in at-risk populations, though dedicated studies are needed to confirm this hypothesis
It considerably improves body weight, insulin resistance, and general cardiometabolic health in addition to reducing blood sugar
Implications for Clinicians: Prescribing Considerations, Future Generics, and Drug Class Evolution Tirzepatide introduces a new era of incretin-based therapy , and clinicians play a key role in ensuring it is used safely and effectively
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