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9 Accordingly, much of the field has focused on intracellular determinants of susceptibility, including cellular iron handling, glutathione metabolism, the remodeling of polyunsaturated fatty acid (PUFA)-containing phospholipids, and both glutathione peroxidase 4 (GPX4)-dependent and GPX4-independent antioxidant defense pathways
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Preprint posted online February 11, doi:10.64898/2026.02.09.26345925 Fransson F, Werneke U, Harju V, et al
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While some research has primarily focused on the pasteurized strain because its cheaper to produce, most human studies showing health benefits of Akkermansia have used live strains
