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A Roux-en-Y gastric bypass (RYGB) , where the stomach is divided, then the small intestine is attached directly to the smaller pouch, bypassing the rest of the stomach

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This study systematically explored the associations between GLP-1RAs and 12 common psychiatric and neurodevelopmental conditions using large-scale GWAS datasets, revealing protective effects against schizophrenia, anxiety disorders, bipolar disorder, bulimia nervosa, PTSD, and autism, with consistent findings across multiple databases for anxiety disorders, autism, and schizophrenia

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The N-terminus of GLP-2, His 1P (P indicates that the residue belongs to GLP-2), which is located above the conserved central polar network of class B GPCRs, is oriented toward TM3 and forms a hydrogen bond with H268 3.37b (Wootten numbering in superscript 27 ) and hydrophobic contacts with V271 3.40b , W340 5.36b and R344 5.40b (Fig