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The phase 1b trial characterised them: mostly ecchymosis (bruising, in 79% of those affected) and redness (32%), all mild, and, critically, not dose-dependent

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Increase tirzepatide to therapeutic dose (12.515mg weekly), ensure 5-amino-1MQ is dosed consistently at 100mg daily, and implement structured dietary intake with adequate protein (1.62.2g/kg) to support the catabolic shift both compounds induce