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In this narrative review, we discuss pharmacological therapeutic options for MASH with a focus on newly approved or promising metabolism-based pharmacotherapies currently being evaluated in late-phase RCTs for the treatment of this common and burdensome liver disease

Introduction# Ecnoglutide (XW003, Sciwind Biosciences) and semaglutide (Novo Nordisk) are both GLP-1 receptor agonists for obesity and type 2 diabetes, but they differ fundamentally in their signaling pharmacology

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Who should use cautionor avoid tirzepatide Tell your clinician if you have or have had: Personal or family history of medullary thyroid carcinoma (MTC) or MEN2 Pancreatitis , significant gallbladder disease , or severe GI disorders (e.g., gastroparesis) Pregnancy or breastfeeding (not recommended)

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It can help reduce the appearance of pigmentation, dark spots, and uneven skin tone, resulting in a brighter and more radiant complexion