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While the peptide functions at a wide range, prolonged exposure to pH below 4.0 reduces efficacy over time

Currently, a 52-week Phase 2 clinical trial (NCT05669599) is underway for the overweight and obese population to further evaluate the safety and long-term efficacy of AMG133

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Some patients report better sleep after weight and sugar control

By stimulating blood vessel growth, the peptide ensures that damaged tissues receive an adequate supply of oxygen and nutrients, while also facilitating the removal of metabolic waste

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