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Acknowledgments The authors gratefully acknowledge the Board of the Instituto da Criana, Hospital das Clnicas, for their institutional support, with special thanks to Dr

Clinical trials : Research studies that test how well a medication works and its safety before it receives FDA-approval or becomes widely available

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Originally developed for diabetes and increasingly prescribed for weight loss, these drugs are not just influencing physical health and body size

10.1126/science.1255555 Science 45 GrafE

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