The DEPs were then classified by GO annotation based on three categories (GO term level 1): biological process, cellular component, and molecular function
Persistent oxidative stress has been linked in research literature to cellular damage affecting lipids, proteins, and DNA
However, the total number of adipocytes is determined in childhood and adolescence, regardless of body mass [23]
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Collectively, this indicates that males may be more vulnerable to the detrimental effects of high-fat or WD in middle age, especially on amygdala-dependent associative conditioning
In addition to metformin, other anti-diabetic drugs belonging to other classes, like TZDs and DPP-4 inhibitors showed encouraging results