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The method optimization takes into account the functional data of GP complex: 1) the peroxilipid is reduced by GSH (reduced glutathione) to hydroxilipids (GP activity)

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Glutathione Glutathione (GSH) is a tripeptide that contains an unusual peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain.It is an antioxidant, preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides

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To determine whether these effects depend on RAMP-containing amylin receptor subtypes (AMY1R and AMY3R), experiments were conducted in HFD-fed WT and RAMP1/3 double knockout (KO) mice

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Photoprotection: against UVB, UVA, UVA1, + blue light

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Most of its going straight down the toilet

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