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In vitro studies suggest that Ipamorelin may activate phospholipase C (PLC), which could stimulate inositol triphosphate (IP3) and diacylglycerol (DAG) pathways
In addition, GBM cells have been shown to activate serine synthesis and one-carbon metabolism to survive glutamine deprivation
The withdrawal pattern typically involves gradual return of appetite over 2 to 4 weeks, followed by weight regain over the subsequent months
Available from: www.karger.com/journals/hre
Conte C et al
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