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Nausea, vomiting, diarrhea, constipation, abdominal pain , and bloating show up regularly in trials and real-world use

Tesamorelin stimulates growth hormone via GHRH receptor activation on the pituitary gland and is FDA-approved for HIV-related lipodystrophy

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Raychaudhuri SK, Maverakis E, Raychaudhuri SP

However, duration varies between individuals, and persistent or worsening tiredness warrants medical evaluation to exclude other underlying conditions

Research consistently shows that when body weight decreases, the body loses both fat mass and lean muscle mass, not fat alone. Muscle plays an essential role in strength, balance, mobility, and metabolic function