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Cancer Res Treat , 50 , 445460

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282 ERAD deficiency in adipocytes leads to the accumulation and aggregation of misfolded LPLs within the ER, which are removed via ER-phagy

Importantly, the cardiometabolic improvements seen during treatment such as healthier blood pressure, cholesterol, and glucose levels also reverted toward baseline after withdrawal

It is crucial for phase II liver detoxification , where toxins are neutralized and prepared for elimination