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Effect of High-Concentration Uric Acid on Nitric Oxide

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The authors concluded that probiotic and prebiotic supplementation exerts measurable antioxidant and anti-inflammatory effects in this model, supporting their potential as complementary neuroprotective strategies ( Supplementation with three different lactobacillus strains to VPA-induced ASD mice improved behavioral symptoms compared to the risperidone group, a drug approved by the Food and Drug Administration

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Cells were treated with either glutathione diethyl ester (GDE) to enhance intracellular GSH or L-buthionine sulfoximine (L-BSO) to inhibit GSH synthesis