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IGF-1 LR3 showed lower affinity to IGF binding proteins and a more potent hypoglycaemic action than IGF-1
However, for people with needle phobia or strong injection aversion, oral semaglutide offers a less effective but viable alternative
[9] [10] However, older adults with severe heart failure or significant renal impairment require careful assessment, as dehydration from gastrointestinal side effects may exacerbate kidney function decline and increase acute kidney injury risk
The choice often comes down to personal preference and lifestyle
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