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[15] Animal studies in vivo An in vivo study in aging mice found that epitalon treatment significantly reduced the incidence of chromosomal aberrations, both for wild-type mice and for mice characterized by an accelerated aging phenotype, which is consistent with increases in telomere length

doi: 10.1001/jama.2020.4006 96 BekkeringSArtsRJWNovakovicBKourtzelisIvan der HeijdenCLiYet al

We next evaluated the levels of H3K27ac, a mark of active cis-regulatory regions, and H3K4me1, mark of active and primed enhancers, in monocytes before and after 1, 4, and 24 hours of BDG exposure

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A 2015 review in the Journal of Aging Research catalogued over 50 human genes GHK-Cu modulates, including those governing DNA repair, antioxidant defense (superoxide dismutase, catalase), and anti-inflammatory signaling 4