Mitochondrial dysfunction that occurs in T2DM is inseparable from the glycolytic pathway, presumably it involves increased ROS production and energy expenditure (Qi et al., 2017)
PubMed Kannengiesser, K., Maaser, C., Heidemann, J., Luegering, A., Ross, M., Brzoska, T., Bohm, M., Luger, T.A., Domschke, W., Kucharzik, T
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(visit source) N Nosaka, Y Suzuki, A Nagatoishi, M Kasai, J Wu, M Taguchi
Renal function affects drug clearance differently depending on the specific GLP-1 receptor agonist