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these data strongly suggest that subjects with idiopathic chronic cholestasis and personal or familial risk factors for inherited cholestasis, as well as DIC, ICP, or LPAC history, should be screened for a panel of primary cholestasis-related genes

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Potent Retinoids (e.g., Tretinoin): Retinoids can be irritating and may increase skin sensitivity, making simultaneous use with GHK-Cu potentially problematic