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Skin and Extracellular Matrix Research Epithalon has been studied in connective tissue and skin-related models focusing on fibroblast function and extracellular matrix integrity: Rodent studies indicate that Epithalon may increase fibroblast activation and proliferation parameters, with reported relative increases in fibroblast activity in certain skin models

doi: 10.1007/s11695-019-03845-0 87 MurphyG.McGuireM

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For proliferation analysis, expanded HBs were fixed with 4% PFA, incubated in blocking and permeabilizing buffers (0.1% Triton X-100, 5% normal donkey serum), and then incubated with APC-conjugated Ki67 and other indicated antibodies [1]