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Activated by ROS, AP-1 regulates gene expression related to oxidative stress and inflammation 72
Its defining chemical feature, and the reason it is studied as a complex, is its high affinity for copper(II)
Do not spray it directly onto the powder
Hederagenin improves renal fibrosis in diabetic nephropathy by regulating Smad3/NOX4/SLC7A11 signaling-mediated tubular cell ferroptosis
Collins et al., 2023)
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