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the FDA itself hasn't formally loosened restrictions yet. The vote came from the PCAC, not the FDA, and their recommendation is strictly advisory, not legally binding. According to Holt, nothing changes for consumers right now simply because the PCACs vote is an advisory one

In February 2025, the FDA declared that Novo Nordisk had increased manufacturing capabilities enough to keep up with demand, and the shortage was over

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Proton magnetic resonance spectroscopy ( 1 H MRS), with its extremely high sensitivity, is used for detecting and quantifying several endogenous tissue metabolites in a single acquisition, but it is not capable of tracking the activity of a metabolic pathway due to limitations related to water, lipid suppression, and magnetic field homogeneity [22]