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Biofactors (2018) 44:14857

Theoretical concerns have been raised regarding GLP-1 medicines and cancer risk, primarily based on animal studies

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101 In patients with T2DM and overweight or obesity, 16 weeks of danuglipron administered twice daily at a maximum dose of 120 mg yielded placebo-adjusted weight loss of up to 4.2 kg and a reduction in mean HbA1c levels of up to 1.2% relative to placebo in the highest dose group