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Diabetes and Metabolic Health GLP-1 medications can help regulate blood sugar by supporting insulin release when glucose levels rise, reducing excess glucagon, slowing digestion, and influencing appetite
REWIND (dulaglutide): 12% MACE reduction over the longest follow-up in the class, 5.4 years
This higher concentration means a smaller injection volume for the same dose, and it also changes how the insulin absorbs into the body, creating a flatter, more prolonged activity profile that can last up to 36 hours
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The five qualifying conditions The five qualifying conditions for the NHS pathway under NICE TA1026 are 4 : Type 2 diabetes High blood pressure (hypertension) Cardiovascular disease (previous heart attack, stroke, angina, or coronary procedure) High cholesterol or dyslipidaemia Obstructive sleep apnoea For the private route, the Mounjaro and Wegovy product licences accept any one of these, plus prediabetes (an HbA1c blood-sugar reading between 42 and 47 mmol/mol) 1,2
