If retatrutide were to receive regulatory approval in future, its pricing would likely be subject to negotiation between the manufacturer (Eli Lilly) and NHS England under the Voluntary Scheme for Branded Medicines Pricing, Access and Growth (VPAG, 2024), as well as appraisal by the National Institute for Health and Care Excellence (NICE) to determine cost-effectiveness
Compounded semaglutide requires manual drawing from a vial with a syringe, while Wegovy pens are pre-filled single-use injectors
This leaves buyers gambling with unknown chemicals, and potentially their lives, in a market that one MP described as alarming
Whether the pill improves adherence "will heavily depend on whether insurers cover this new form of semaglutide and also the pricing for direct-to-consumer sales for this medication," says Gasoyan.
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