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Infectious AEs were classified by high-level group terms (HLGTs), high-level terms (HLTs), and preferred terms (PTs) based on the Medical Dictionary for Regulatory Activities (MedDRA), then ranked by frequency and signal strength

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This approach helps minimize the risk of side effects such as nausea, vomiting, diarrhea, or bloating, and makes the treatment more sustainable

Participants were recruited from research centers located in Salvador, Bahia, Valinhos, and Bernardo do Campo, So Paulo, Brazil

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For patients who cannot tolerate minoxidil, or who prefer a non-pharmaceutical approach, this meta-analysis provides the highest level of evidence supporting microneedling as a legitimate first-line treatment