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This breadth may reflect the fundamental nature of the pathways being studied, such as endothelial function, cell migration machinery, and stress-response biology, rather than a single tissue-specific receptor mechanism

Semen quality and human fertility: a prospective study with healthy couples

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They bind with the pumps directly or indirectly

This part is derived from a -barrel in CE-clan proteases, which is surrounded by -helices on both sides, forming an -helical bundle in CE-clan proteases (Fig