However, a recent retrospective cohort study using a nationwide commercial administrative claims database including 6,806,046 patients with T2DM who underwent outpatient upper endoscopy from 2005 to 2021reported contrasting findings
Yeo and colleagues explained that with rising obesity in the U.S., the increasing prevalence of GLP-1 receptor agonists prescribed for obesity may contribute to drug shortages. Further, drug shortages may exacerbate the existing nationwide racial and ethnic disparities in GLP-1 receptor agonist prescriptions, they wrote, adding that the results suggest a call for strategies to address the growing demand and ensure equitable access to the drugs.
Complaints on Reddit and the BBB mention slow customer service and difficulty getting refunds, especially if they decide not to proceed with medication
ACS Mater Au
Although oral Semaglutide offers a non-injectable dosing option, it faces a number of challenges, notably bioavailability, metabolic stability, and gastrointestinal side effects (Ke et al., 2024) (Table 2)
How Do Their Mechanisms Differ