QZ: Methodology, Writing review and editing
Glutathione has many functions within the body including, supporting immune function, forming sperm cells, fighting free radicals, helping with certain enzyme functions, and making DNA
Rather than forcing cellular processes, it simply removes obstacles to natural repair mechanisms
We will focus on the dysregulation of ubiquitination and proteasomal degradation in neurodegenerative pathology in AD, PD, and HD ( Table 1 )
Specifically, we are interested in the following themes: Novel therapeutic target(s) for psoriatic disease Recently (last 5 years) approved therapies for psoriatic disease Biosimilars - role in psoriatic disease Safety profile of newer therapies Economic impact of newer therapies on health system Newer mode of drug-delivery system in psoriatic disease Therapeutic prospect of small molecules in psoriatic disease Therapeutic guidelines to combine newer therapies with conventional therapy in psoriatic disease Plant derived compounds in psoriatic disease Pathophysiology and therapies in the future of psoriasis and psoriatic arthritis treatment Psoriasis and psoriatic arthritis are complex autoimmune diseases affecting ~2-3% of world population
Aleksovska, K