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Moreover, the greater stability of the Cagri-induced bypass conformation relative to the rAmy-induced bypass conformation, when engaged with the CTR, is likely a major contributor to the increased conformational stability of the Cagri-AMY 2 R-Gs complex relative to the rAmy-AMY 2 R-Gs complex

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While sensitivity analyses excluding such studies did not materially alter the results, transparency in reporting trial methodology remains a key requirement for future research