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OS can damage oocytes in developing follicles, oocytes and spermatozoa in the peritoneal cavity, or embryo in fallopian tube [17, 153] or through redox (pro-oxidant and antioxidant) imbalance

Although the FDA has yet to approve a closed-loop artificial pancreas system, research is ongoing and these devices will likely become increasingly available in the coming years as technology improves (FDA 2016)

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