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Confirmatory trials are needed to confirm clinical benefit for these drugs to remain on the market

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Combining GLP-1 receptor agonists is generally contraindicated

The three substandard drugs tested came from three different illegal online pharmacies, which sold them as generic semaglutide drugs for weight loss, appetite suppression, diabetes, and cardiovascular health

Retatrutide, Eli Lilly's next-generation triple agonist, achieved 28.328.7% across two completed Phase 3 trials