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Severe nausea on GLP-1 medications combined with illness-related vomiting creates a dangerous situation where: Dehydration can develop rapidly You cannot absorb oral medications or nutrients The GLP-1 medication may worsen gastrointestinal symptoms Risk of electrolyte imbalances increases When to seek emergency care : If you cannot keep any fluids down for 12+ hours, notice dark urine, feel dizzy upon standing, or have a rapid heartbeat, seek medical attention immediately
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However, the half-life of GLP-1 is too short at 1 to 2 minutes, making it difficult to use as a drug [21]
Beyond 5 months: Full effect at maintenance dose The full appetite-suppressing effect usually becomes most noticeable after several months, once dosing is stable
These fatty acids seem to play a role in reducing appetite and food intake
