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Collectively, these results highlight Claudin-7 as an essential regulator of intestinal barrier integrity and epithelial proliferation, and suggest that its loss predisposes the intestine to inflammation-driven dysplasia and tumorigenesis (Xu et al., 2019)
Reticence to go down the obesity path is also borne out by the length of time it took for Eli Lilly to commit to the issue even though they took out a patent early on for many different types of GLP-1, including for the treatment of obesity
Protein First: Protecting Muscle While You Lose Weight When weight comes off quickly and protein intake is low, some of what you lose can be lean muscle the very thing that keeps your metabolism strong
While estrogen and cortisol are not standard lab tests for patients taking GLP-1 medications (unless the patient has pre-existing conditions like PCOS or an adrenal disorder or is exhibiting specific symptoms), there is a growing body of research that indicates the drugs can affect and interact with these hormones, especially in certain patient populations, like women navigating menopause
Traditional weight loss programs often include weight loss measures like dieting and exercising to reach your weight loss goals
dose reduction or medication discontinuation may be necessary to prevent complications
