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These findings hold particular relevance for GLP-1 non-responders, providing crucial insights into alternative treatment pathways
You may qualify if you have a BMI of 30 or higher, or 27+ with weight-related conditions
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A post hoc analysis of SUSTAIN 6 showed that the beneficial effect of s.c semaglutide vs placebo on MACE was not dependent on the gender, age or baseline CV risk profile of subjects [45]
Metsera has a nice slide on this below, and assuming their calculations are true, this COGs delta could prove to be a valuable commercial advantage
That matters because weight loss does not necessarily equate to better health, especially if too much of that loss comes from the muscle
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