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The reduction in homocysteine levels leads to a reduction in methionine levels and methionine synthase activity: The decrease in the methionine synthase activity thus creates the well-established methyl trap, as a consequence of the one-way kinetics of 5-MTHF synthesis [Figure 2]

Engineering nanoparticles for targeted delivery of nucleic acid therapeutics in tumor

Abbreviations Traumatic brain injury, TBI