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No published study has linked it to tumor promotion, but if you have an active malignancy, the theoretical risk of feeding blood vessels to a tumor is worth taking seriously

commonly reported issues from anecdotal and preclinical sources include injection-site irritation, fatigue or flu-like symptoms, muscle tightness/cramps, temporary water retention, and theoretical immune reactions to the PEG component

doi: 10.1016/j.bbamcr.2025.120054 83 LuoLCaiYJiangYGongYCaiCLaiDet al

BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage

Consistency and healthy lifestyle habits can help maximize the benefits of treatment