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It improves insulin sensitivity, which shifts your body metabolic machinery toward fat utilization rather than fat storage

(PubMed) Petersen RC, Thomas RG, Grundman M, et al

Thyroid patients with Hashimotos have a problem: Hashimotos causes thyroid damage, which causes thyroid problems leading to a sluggish metabolism and weight gain

Sodium-glucose cotransporter 2 inhibitors (SGLT2-I) and glucagon-like peptide-1 receptor agonists (GLP-1RA) have been shown to reduce cardiovascular risk and mortality in patients with type 2 diabetes mellitus (T2D) and established cardiovascular disease, yet remain underutilized in clinical practice

Indeed, the increased thrombotic risk caused by hyperhomocysteinemia, recently reviewed by D'Angelo and Selhub (1997), seems to be independent of the conventional risk factors including protein C, protein S, and antithrombin III deficiencies

In both forms, semaglutide starts working immediately, but results dont happen overnight