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But heres what makes it different from every other GLP-1 drug out there: its a small molecule

As the body adjusts to a new weight and lower muscle mass, joints and muscles may feel sore or stiff for a period of time

Patients treated with semaglutide or any GLP-1 analogue in combination with a sulphonylurea or insulin may have an increased risk of hypoglycaemia (low blood glucose of less than 4mmol/l or 72mg/dl)

For patients, it marks a much-needed shift away from willpower-based narratives and toward understanding weight as something rooted in biology

Do not change a dose because of social media advice, a weight-loss target, or a friends experience

A medication called tirzepatide , marketed under the brand name Mounjaro